| SNES | Star Trek Next Generation : Future's Past | 1995 | Aventure, Stratégie |
| SNES | Stardust Suplex | 1995 | Sport |
| SNES | Starfox | 1993 | Shoot-em-up |
| SNES | Starfox 2 (BETA) | ? | Shoot-em-up |
| SNES | StarFox Super Weekend Competition | 1993 | Shoot-em-up |
| SNES | Stargate | 1994 | Action, Plateforme |
| SNES | Stealth | 1992 | Wargame |
| SNES | Steel Talons | 1993 | Simulation |
| SNES | Sterling Sharpe : End 2 End | 1995 | Sport |
| SNES | Steven Seagal is The Final Option (version BETA) | 1994 | Beat-em-all |
| SNES | Stone Protectors | 1994 | Beat-em-all |
| SNES | Street Combat | 1993 | Versus fighting |
| SNES | Street Fighter 2 | 1992 | Versus fighting |
| SNES | Street Fighter 2 Turbo | 1993 | Versus fighting |
| SNES | Street Fighter Zero 2 | 1996 | Versus fighting |
| SNES | Street Hockey 95 | 1994 | Sport |
| SNES | Street Racer | 1994 | Course |
| SNES | Strike Gunner | 1992 | Shoot-em-up |
| SNES | Striker | 1993 | Sport |
| SNES | Stunt Race FX | 1994 | Course |
| SNES | Sugoro Quest ++ Dicenics | 1994 | Jeu de plateau |
| SNES | Sugoroku Ginga Senki | 1996 | Jeu de plateau |
| SNES | Sun Sport Fishing : Keiryuu Ou | 1994 | Sport |
| SNES | Sunset Riders | 1993 | Action, Plateforme |