| MD | Spirou | 1995 | Plateforme |
| MD | Splatterhouse 2 | 1992 | Beat-em-all |
| MD | Splatterhouse 3 | 1993 | Beat-em-all |
| MD | Sports Talk Baseball | 1992 | Sport |
| MD | Star Control | 1991 | Plateforme |
| MD | Star Cruiser | 1990 | Aventure, Tir |
| MD | Star Trek: Deep Space Nine: Crossroads of Time | 1995 | Aventure |
| MD | Star Trek: The Next Generation: Echoes from the Past | 1994 | Aventure, Stratégie |
| MD | Starflight | 1991 | Simulation |
| MD | Stargate | 1994 | Action, Plateforme |
| MD | Steel Talons | 1992 | Simulation |
| MD | Stormlord | 1990 | Action, Réflexion |
| MD | Street Fighter II: Special Champion Edition | 1993 | Versus fighting |
| MD | Street Racer | 1994 | Course |
| MD | Street Smart | 1990 | Versus fighting |
| MD | Streets of Rage | 1991 | Beat-em-all |
| MD | Streets of Rage 2 | 1992 | Beat-em-all |
| MD | Streets of Rage 3 | 1994 | Beat-em-all |
| MD | Strider | 1990 | Arcade |
| MD | Strider II | 1993 | Arcade |
| MD | Striker | 1995 | Sport |
| MD | Sub-Terrania | 1994 | Shoot-em-up |
| MD | Summer Challenge | 1993 | Sport |
| MD | Sunset Riders | 1992 | Arcade |